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Black hellebore (Helleborus niger, Helleborus nigra)
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Black hellebore/Drug Interactions:- Cardiac glycosidesCardiac glycosides: Black hellebore contains cardiac glycosides, which have a similar action as foxglove (Digitalis spp.), a cardiac stimulant.
- DigoxinDigoxin: Black hellebore contains cardiac glycosides, which have a similar action as foxglove (Digitalis spp.), a cardiac stimulant.
- Diuretics, potassium depletingDiuretics, potassium depleting: Black hellebore contains cardiac glycosides; theoretically, concomitant use of black hellebore and potassium depleting diuretics may lead to decreased potassium levels.
- Gastrointestinal agentsGastrointestinal agents: According to secondary sources, black hellebore may cause gastrointestinal irritation.
- NarcoticsNarcotics: The root and leaves of various species of Helleborus contain the glucoside helleborin, a narcotic poison.
- QuinineQuinine: Black hellebore contains cardiac glycosides, which theoretically may interact with quinine, a cardiac depressant.
- Stimulant laxativesStimulant laxatives: According to secondary sources, black hellebore may cause gastrointestinal irritation.
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Black hellebore/Herb/Supplement Interactions:- Cardiac glycosidesCardiac glycosides: Black hellebore contains cardiac glycosides, which have a similar action as foxglove (Digitalis spp.), a cardiac stimulant.
- Cinchona (Cinchona pubescens), quinineCinchona (Cinchona pubescens), quinine: Black hellebore contains cardiac glycosides, which theoretically may interact with quinine, a cardiac depressant.
- Diuretics, potassium depletingDiuretics, potassium depleting: Black hellebore contains cardiac glycosides; theoretically, concomitant use of black hellebore and potassium depleting diuretics may lead to decreased potassium levels.
- Foxglove (Digitalis spp.), digoxinFoxglove (Digitalis spp.), digoxin: Black hellebore contains cardiac glycosides, which have a similar action as foxglove (Digitalis spp.), a cardiac stimulant.
- Gastrointestinal agentsGastrointestinal agents: According to secondary sources, black hellebore may cause gastrointestinal irritation.
- HorsetailHorsetail: Both black hellebore and horsetail contain cardiac glycosides, which may cause potassium depletion.
- LicoriceLicorice: Both black hellebore and licorice contain cardiac glycosides, which may cause potassium depletion.
- Stimulant laxativesStimulant laxatives: According to secondary sources, black hellebore may cause gastrointestinal irritation.
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Black hellebore/Food Interactions:- Insufficient evidence available.
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Black hellebore/Lab Interactions:- Cardiac function testsCardiac function tests: Black hellebore contains cardiac glycosides, which have a similar action as foxglove (Digitalis spp.), a cardiac stimulant. Therefore, black hellebore may interfere with tests to measure cardiac function.
- Gastrointestinal function testsGastrointestinal function tests: According to secondary sources, black hellebore may cause gastrointestinal irritation. Therefore, black hellebore may interfere with tests to measure gastrointestinal function.
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Copyright © 2011 Natural Standard (www.naturalstandard.com)
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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
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